Author: Frank Domino, MD in collaboration with Aylin Madore, MD
I stay up-to-date on the latest COVID-19 news and am regularly compiling a list of articles published that are relevant to your primary care practice. Read the insights below from recently published articles in less than two minutes.
COVID-19 Update: FDA Broadens Emergency Use Authorization for Veklury (Remdesivir) to Include All Hospitalized Patients for Treatment of COVID-19
Recently (August, 28 2020) the US FDA granted emergency authorization to use remdesivir in all hospitalized patients with COVID-19 despite the drug’s limited data or mortality benefit.
Effect of Remdesivir vs Standard of Care on Clinical Status at 11 Days in Patients With Moderate COVID-19
In a recent industry-sponsored trial of 584 patients with moderate COVID-19 (defined as hospitalized with evidence of COVID-19 pneumonia but no hypoxia), patients were randomized to 10 days of remdesivir, 5 days of remdesivir, or standard care with outcomes measured at “Day 11” on a 7-point ordinal scale. Those in the 5-day arm had significantly better scores than those in the 10-day arm or control groups; in all groups, there were no significant differences in time to recovery, time to improvement in clinical status, or death at 28 days.
A cohort study and case investigation found that individuals who rode a bus to a worship event with a patient with COVID-19 had a greater risk of developing SARS-CoV-2 infection than individuals who rode a separate bus to the same worship event.
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