Author: Frank Domino, MD in collaboration with Aylin Madore, MD

I stay up-to-date on the latest COVID-19 news and am regularly compiling a list of articles published that are relevant to your primary care practice. Read the insights below from recently published articles in less than two minutes.

COVID-19 Update: FDA Broadens Emergency Use Authorization for Veklury (Remdesivir) to Include All Hospitalized Patients for Treatment of COVID-19

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Recently (August, 28 2020) the US FDA granted emergency authorization to use remdesivir in all hospitalized patients with COVID-19 despite the drug’s limited data or mortality benefit.

Effect of Remdesivir vs Standard of Care on Clinical Status at 11 Days in Patients With Moderate COVID-19

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In a recent industry-sponsored trial of 584 patients with moderate COVID-19 (defined as hospitalized with evidence of COVID-19 pneumonia but no hypoxia), patients were randomized to 10 days of remdesivir, 5 days of remdesivir, or standard care with outcomes measured at “Day 11” on a 7-point ordinal scale. Those in the 5-day arm had significantly better scores than those in the 10-day arm or control groups; in all groups, there were no significant differences in time to recovery, time to improvement in clinical status, or death at 28 days.

Community Outbreak Investigation of SARS-CoV-2 Transmission Among Bus Riders in Eastern China

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A cohort study and case investigation found that individuals who rode a bus to a worship event with a patient with COVID-19 had a greater risk of developing SARS-CoV-2 infection than individuals who rode a separate bus to the same worship event.

For more insights, view our collection of COVID-19 resources and CME courses. We recognize it is critical that you have access to timely, reliable information, so we are working hard to release new content in collaboration with our team of infectious disease experts, medical specialists, and primary care clinicians like Dr. Frank Domino.