Author: Bryan Legere

The ever-insightful George Costanza must have been talking about e-cigarettes when he opined, “This thing is like an onion. The more layers you peel, the more it stinks.”

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Opioid misuse and overdose is an ongoing epidemic and public health emergency in the United States. Almost 850,000 people have died from a drug overdose since 1999.1 Over 70,000 people died in 2019, and 70% of them involved an opioid.1 This article will detail the rise of the opioid epidemic, highlight how educational and governmental institutions have responded to the crisis through education campaigns directed toward clinicians, and describe the Centers for Disease Control’s (CDC) guidelines for prescribing opioids for chronic pain in the United States.

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Drug overdose is the leading cause of injury-related death in the United States. In 2019, over 70,000 people died from a drug overdose, and over 70% involved a prescription or illicit opioid. Prescription opioid use has been a significant contributor to the opioid epidemic since the early 2000s.

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It’s that time of year again. As reliably as Tom Brady secures a spot in the playoffs every winter, the American Diabetes Association (ADA) releases its annual updates to the Standards of Medical Care in Diabetes. This year’s recommendations offer several key changes.

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Migraine is a widespread neurologic problem. It affects 1 billion people worldwide and almost 40 million people in the United States.1 The primary care clinician needs to understand the management options for preventing and acutely treating migraine. In this article, learn about the epidemiology of migraine, the pathophysiologic mechanisms behind migraine pain, options for the prevention and acute treatment of migraine, and the newest FDA-approved agents.

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As you may already know, the use of preexposure prophylaxis (PrEP) has been proven safe and effective in reducing the risk of sexual HIV acquisition. The problem is that it’s not getting prescribed to everyone who needs and wants it.

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In a study that will inevitably be made into a Hallmark movie, researchers have uncovered a remarkable phenomenon: when long-time couples are in close proximity to each other, their heart rates sync up like a crowd of strangers catching the first beats of “We Will Rock You.”

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We’ve assumed for months that Adele’s new album would take our breath away, but as of this week, our ears can finally confirm its Adele-level quality. Similarly, we’ve assumed consuming zinc could help fight a respiratory infection, but we now have published data to substantiate that claim.

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As if we needed another reason to avoid fast food, preliminary research suggests that traces of plastic in fast-food products are as ubiquitous as that feeling of regret 30 minutes later.

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We enjoy a hearty debate. Did Tony Soprano die in the finale? Could Ferris Bueller really have completed all those activities before dinner? Can a patient with obesity still be in good health?

Two researchers say most likely to that last one. They combed through a mountain of literature on dieting, exercising, and mortality and examined >200 meta-analyses and single studies. That’s enough data to make Steve Kornacki don his khakis and election-night game-face.

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